Cryotherapy, also called cryosurgery, cryoablation or targeted cryoablation therapy, is a minimally invasive treatment that uses extreme cold to freeze and destroy diseased tissue, including cancer cells. During cryotherapy, liquid nitrogen or argon gas is applied to diseased cells located inside the body. Our physicians have been using minimally invasive cryoablation techniques for select cases of kidney and prostate cancer over the past several years.